Facing issue in opening task of integration package

Facing issue in opening task of integration package

Facing issue in opening task or creating new task for integration package

it is saying please provide a valid connection (and showing time out)

while in edit and test connection every thing is fine and says connection is valid.

not sure what is the issue suddenly
a couple of hour before every thing was working fine.
I noticed this issue some time before also and solved after some time, but this is serious when you are performing activities time bound with commitments.

please provide some input if any.

Many thanks in advance
Vivek